Which two medications can be used to treat oral candidiasis?

Fluconazole and Nystatin are both effective treatments for oral candidiasis, a fungal infection caused by the overgrowth of Candida species in the mouth. Fluconazole, an oral antifungal medication, works systemically to inhibit the growth of fungi by interfering with their cell membrane synthesis. It is particularly effective against various strains of Candida and is often prescribed for moderate to severe cases of oral candidiasis.

Nystatin is an antifungal that is used topically or orally and directly targets the Candida organisms in the mucosal membranes. It binds to ergosterol in the fungal cell membrane, causing the cell contents to leak out and leading to cell death. It is especially useful for localized infections like oral thrush.

In contrast, the other combinations of medications listed may not be as effective or suitable for treating oral candidiasis specifically. Amphotericin B and Griseofulvin are primarily used for systemic fungal infections and dermatophyte infections, respectively, while Caspofungin and Voriconazole are reserved for more severe invasive fungal infections and do not target oral candidiasis specifically. Clotrimazole and Ketoconazole, while antifungal, may not be as commonly used in the context of oral candidiasis compared to the combination