Which medication is specifically indicated for treating oral candidiasis?

Nystatin is specifically indicated for treating oral candidiasis due to its localized antifungal properties targeted towards Candida species, which commonly cause this condition. Nystatin works by binding to the ergosterol in the fungal cell membrane, leading to increased permeability and ultimately cell death. This mechanism is particularly effective in the oral cavity, where the organism can thrive and cause infection.

While fluconazole and itraconazole are effective antifungal medications that can also treat various forms of candidiasis, they are generally reserved for systemic infections and more severe cases. Terbinafine is primarily used to treat dermatophyte infections and is not effective against Candida species. Therefore, Nystatin is the most appropriate choice for localized infections like oral candidiasis.