Which drug class includes Ketoconazole and Fluconazole?

Ketoconazole and Fluconazole belong to the class of antifungal medications known as imidazoles and triazoles. This class of drugs is primarily used to treat fungal infections by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes.

Both Ketoconazole and Fluconazole target the same biochemical pathway, thus affecting the integrity of the fungal cell membrane and ultimately leading to the death of the fungus. Their effectiveness against a variety of fungal pathogens makes them important in clinical settings.

In contrast, other classes listed, such as polyenes (which include drugs like Amphotericin B), echinocandins (such as Caspofungin), and antibacterials (which are used to treat bacterial infections), do not include Ketoconazole and Fluconazole, clarifying that the correct classification for these two drugs is indeed imidazoles and triazoles. This knowledge is crucial for understanding antifungal therapy and making informed decisions about treatment options.