What substance should a client avoid taking with tetracycline to prevent reduced absorption?

Tetracycline is an antibiotic that can have impaired absorption when taken with certain substances, primarily those containing calcium, magnesium, or iron. Milk is high in calcium, which binds to tetracycline and forms insoluble complexes, leading to decreased absorption of the medication in the gastrointestinal tract. Consequently, this can significantly reduce the effectiveness of the drug.

While orange juice, coffee, and water do not contain significant amounts of calcium or the other minerals that would interfere with tetracycline absorption, milk's calcium content is particularly problematic. Therefore, it is essential for patients taking tetracycline to avoid milk and other dairy products to ensure proper drug absorption and treatment efficacy.