Oral forms of acyclovir are most effective for herpes infections to achieve which two outcomes?

The choice emphasizes that oral forms of acyclovir are effective in decreasing pain and shortening healing time for herpes infections. Acyclovir is an antiviral medication that targets the replication of the herpes simplex virus. When administered orally, it helps alleviate the discomfort associated with herpes lesions, leading to a reduction in pain.

Additionally, acyclovir works to inhibit the virus's ability to multiply, which ultimately shortens the duration of an outbreak and promotes faster healing of the lesions. By effectively managing both the symptoms and the duration of the infection, patients can experience significant relief and improved outcomes during an outbreak.

The other options do not align with the established effects of acyclovir. For instance, enhancing virus replication contradicts the drug's function; similarly, boosting the immune response is not a direct effect of acyclovir, and facilitating viral spread goes against the intended use of antiviral treatments.